You can’t just rename it to .jpg . The good news: You can extract high-quality JPG images from it.

| Tool | Platform | How to use | |------|----------|-------------| | (free trial) | Windows | Drag IS2 → Right-click image → "Export as JPEG" | | MicroDicom (free) | Windows | File → Open IS2 → File → Save as JPEG | | IrfanView + DICOM plugin | Windows | Install plugin, open IS2, Save As JPG | | Weasis (open-source) | Windows/Mac/Linux | Open IS2 → Export → JPEG |

If you’ve stumbled upon a file with the .is2 extension, you’re likely dealing with medical imaging data —specifically from Olympus OER-Pro or similar endoscopy/capsule endoscopy systems. Unlike a standard photo, an IS2 file often contains a video sequence, patient metadata, or proprietary compression.